QUESTIONS AND ANSWERS
What is the difference between ReGen and other clinics?
We are the only clinic in NZ offering pure expanded stem cell therapy.
This is not a same-day procedure. Our point of difference is that after taking 50 grams or a teaspoon of fat from patients, we extract the stem cells and then multiply them in our lab for up to 8 weeks.
We can grow them to massive numbers, number in the hundreds of millions. The point is that when the patients own cells are injected back into the area of injury they are getting up to 80 million stem cells per joint. Only at this number is there a chance for the cartilage to regrow.
To ensure our lab procedures and expanded cell quality and viability is at a consistently high level we send a sample of every patient's expanded cells to an independent laboratory in Australia where they test and verify the Mesenchymal cells. This is called characterisation and this way we know exactly what is being injected back into our patients.
This cell characterisation also provides us with additional data to map significant success markers.
So the big difference is that you grow the patients’ cells in your lab for 6-8 weeks?
Trials have shown that in order for the potential of cartilage regrowth you need to reinject a large number of Mesenchymal cells. The cells must be expanded in a lab over weeks and once out of the lab, reinjected within a matter of hours.
This cannot be achieved in a same-day procedure.
Under normal stem cell treatments done by non-expanded clinics you can reinject up to 3-5 million stem cells but we are often putting up to 100 million targeted expanded cells into a single joint. This means patients not only get anti-inflammatory properties but at that expanded number our patients get a much better outcome and cartilage regrowth has the highest chance of happening.
What’s wrong with surgery?
At ReGen we believe surgery should be the last option not the first.
For many of those suffering indescribable pain caused by OA, they are lead to believe surgery is the only option. The lack of surgeons to carry out replacement surgeries in NZ can mean being placed on a waiting list. This on top of recovery times and rehabilitation means that some are reluctant to undergo joint replacement surgery.
Our Pure Expanded Stem Cell therapy is getting excellent results and we are confident that we can offer the growing aging population a non-invasive, non-surgical alternative using their own body matter that can give the quality of life back.
We urge those considering surgery to research stem cells as a way to allow their body to use its own matter to heal.
What are your results?
Our current autologous treatments for OA have shown the potential to provide;
- Substantial pain relief
- Improvement in function
- Halting of disease progression
- Potential of delaying and/ or possibly eliminating the need for expensive joint replacement
- Our MRIs show regeneration is possible and does occur
Specialist Sports Physicians report that the clinical results of the treatments are far superior to any other alternative treatments for OA. There have been no reports of any serious adverse events.
Sports stars regularly seek us out to repair a reoccurring injury or to elongate careers. We have treated All Blacks to golfers, martial arts to timbersports world champions.
Regen’s expertise, investment, facilities and Australasian backing with some of the best brains in the regenerative medicine world make us the leader in NZ’s developing industry.
PESC treatment shows cartilage regenerating reversing damage caused by degenerative conditions.
There is a perception that such therapy costs a lot of money
One joint is $12,500 and two of the same joint is $15,000 including GST.
Single knee joint surgery is between $21,000-29,000.
Because we have both a clinic and a lab and control our own procedures from extraction to expansion, we can store patients’ excess cells for further treatments on other joints in years to come. There is no need for future lipoharvests.
Is treatment covered by insurance or ACC?
A big breakthrough for ReGen early in 2019 saw two insurers in NZ accept our patients’ claims for Expanded Stem Cell Therapy.
ACC has also covered the cost of the initial consultation.
This is a major breakthrough for ReGen and all those suffering with debilitating conditions as this means that PESC therapy may soon be recognised as an alternative to surgery.
It is a very positive sign that our consistent results and a heightened awareness of the potential regenerative medicine means PESC therapy will become a commonplace treatment in the future.
What are stem cells?
Stem cells are cells that have the potential to develop into many different cell types in the body. We use your own fat cells as they can develop into any needed cell type, unlike bone marrow cells. They serve as a repair system and can in our specialised lab be multiplied into millions of cells. When placed in a joint they can stimulate the cartilage.
Where do you get the stem cells from?
We get them from your own fat in a process called harvesting the cells. When cells come from your own body they are known as autologous. This minimises the risk of rejection because we start with your own cells. At ReGen we only use a patient’s own cells.
What is the process of harvesting stem cells?
A qualified specialist will take the fat sample in an accredited operating theatre under local anesthesia. The process taking around an hour. In our Queenstown laboratory, the mesenchymal stem cells are extracted, purified and expanded. There’s very little pain involved in the stem cell harvest, dissolving stitches are used. Patients need to avoid anti-inflammatory medicines like ibuprofren or voltaran or celebrex for two weeks prior to the procedure. Note: patients will not be able to drive home.
What is PESC (pure expanded stem cells)?
Our proprietary process means the Mesenchymal stem cells are extracted, purified and not mixed with any other types of stem cells. Expanded means the cells are multiplied and cultured to as many as are needed for your particular case. We typically grow up to 100 million cells for a single joint. Those millions of mesenchymal stem cells represent the most concentrated form of stem cells available in the market today.
Am I a candidate for stem cell therapy?
If you have osteoarthritis or injury that has not recovered and continues to cause pain, you may be. While there is a lot of information on our site, it may be best to ring the clinic and talk through your own requirements. We can advise whether a consult with Dr Mubark would be beneficial. If you are pregnant or have active cancer, stem cell therapy is contraindicated.
Will insurance cover stem cell therapy?
In early 2019 two insurance companies covered the cost of our PESC therapy. Please contact your insurer to see if you qualify.
What happens after my PESC therapy?
After the injection, there may be some minor pain and swelling. Minor inflammation occurs as part of the healing process when the cartilage interacts with stem cells, potentially stimulating cartilage growth. Crutches will be provided to knee patients. Avoid applying ice after the procedure as this can damage cells. A prescription for pain medication will be provided. Paracetamol is recommended. No anti-inflammatory medicines like ibuprofren or voltaran or celebrex should be taken for 4 weeks as this will reduce the potency of the stem cells.
How to achieve optimal results after stem cell therapy?
After the injection we recommend a week’s rest and a joint brace. During your initial consultation the doctor will determine which of the brace types we offer is recommended. We also have partnered with selected physiotherapists to develop a dedicated rehabilitation program. This is specially designed to integrate the stem cells into your joints and to keep the area stable. You can return to normal walking after two weeks. After a month you can run and resume full activities. Alignment braces should be used three months for support during weight-bearing activities. We also recommend taking both Curcumin and Boswellia which are herbal supplements that reduce inflammation and increase healing and blood flow.
Can I travel after stem cell harvesting?
Yes. After the harvest we can cryo-store your cells for up to one year at no charge. When you return you can schedule your injection for a time that fits easily into your schedule.
Can you inject more than one joint or area in the same session?
Yes, we can. This will be discussed during the initial consult. We commonly encounter two knees or two hips. In addition, multiple small joints in the hands and feet can be injected in one prolonged session. Any combination of areas to be treated together can be considered.
Can I have the fat sample and the stem cell injection all in Auckland?
Yes, you can. The initial consultation, harvest, and injection are all in Auckland. After your consult, you’ll be scheduled to have your fat sample taken in one of our many accredited operating theatres. Your sample will be securely sent to our Queenstown laboratory for culturing. When ready (6-8 weeks) we’ll contact you to schedule your injection appointment, in the same location as your first consult.
Do you guarantee success?
We only accept patients who show the best promise of a successful outcome. No therapy or intervention can guarantee 100% success. Our results across all PESC interarticular treatments show 70-90% reduction in pain, increased mobility and in some cases cartilage regeneration.
What are the risks with PESC?
Complications are rare and minor. The most common is pain and irritation at the injection site which lasts for 2-3 days. Infection is rare as the sample is sterilized and sterile conditions are maintained during the injection. At ReGen we only use our patient’s own cells which means they cannot be rejected.
Do stem cells regrow cartilage in all patients?
Our proprietary PESC therapy contains the highest dosage of MSCs in any therapy today.
We use the best injecting techniques under ultrasound guidance to ensure the cells are injected deep into the joints or affected area by our experienced doctor. The regrowth of cartilage takes some time and we recommend redoing scans at 6-12 months after therapy. PESC provide other results in addition to potential regrowth. Over 80% of patients report less stiffness, reduced pain and improved range of motion.
Can stem cells be stored and how much does it cost?
Yes, we can store the cells in cryopreservation for 1 year at no extra cost. In addition, we can keep them for up to 15 years in the lab at a cost of $300 billed annually. The upside is that these younger stem cells will be available if needed in the future.
Can you repeat the process of injecting the same area or another area in the future and does it cost me anything?
If the original cells have been stored with us, we can repeat the injection for up to 15 years. As the cells will need to be expanded into number big enough for regeneration, there will cost involved.
Do you inject stem cells into the spine?
No, not at this stage. Currently, we do all upper and lower limbs, as well as large, medium and small joints.