What is the difference between ReGen and other clinics?

We are the only clinic in NZ offering pure expanded stem cell therapy.

This is not a same-day procedure. Our point of difference is that after taking 50 grams or a tablespoon of fat from patients, in our laboratory we extract the Mesenchymal stem cells and then grow or expand them for up to 6 weeks.

We can grow them to massive numbers, number in the hundreds of millions. The point is that when the patients own cells are injected back into the area of injury they are getting a minimum of 80 million stem cells per joint. Only at this number is there a chance for the cartilage to regrow.

To ensure our lab procedures and expanded cell quality and viability is at a consistently high level we send a sample of every patient's expanded cells to an independent laboratory in Australia where they test and verify the Mesenchymal cells. This is called characterisation and this way we know exactly what is being injected back into our patients.

This cell characterisation also provides us with additional data to map significant success markers.

So the big difference is that you grow the patients’ cells in your lab for 6 weeks?

Trials have shown that in order for the potential of cartilage regrowth you need to reinject a large number of Mesenchymal stem cells. The cells must be expanded in a lab over weeks and once out of the lab, reinjected within a matter of hours.

This cannot be achieved in a same-day procedure.

Under normal stem cell treatments done by non-expanded clinics you can reinject up to 3-5 million stem cells but we are often putting up to 100 million targeted expanded cells into a single joint. This means patients not only get anti-inflammatory properties but at that expanded number our patients get a much better outcome and cartilage regrowth has the highest chance of happening.

What’s wrong with surgery?

At ReGen we believe surgery should be the last option not the first.

For many of those suffering indescribable pain caused by OA, they are lead to believe surgery is the only option. The lack of surgeons to carry out replacement surgeries in NZ can mean being placed on a waiting list. This on top of recovery times and rehabilitation means that some are reluctant to undergo joint replacement surgery. 

Our Pure Expanded Stem Cell therapy is getting excellent results and we are confident that we can offer the growing aging population a non-invasive, non-surgical alternative using their own body matter that can give the quality of life back.

We urge those considering surgery to research stem cells as a way to allow their body to use its own matter to heal.

What are your results?

Our current autologous treatments for OA have shown the potential to provide;

  • Substantial pain relief
  • Improvement in function
  • Halting of disease progression 
  • Potential of delaying and/ or possibly eliminating the need for expensive joint replacement
  • Patient x-rays and MRIs show regeneration is possible and does occur

Specialist Sports Physicians report that the clinical results of the treatments are far superior to any other alternative treatments for OA. There have been no reports of any serious adverse events. 

Sports stars regularly seek us out to repair a reoccurring injury or to elongate careers. We have treated All Blacks to golfers, martial arts to timbersports world champions.

Regen’s expertise, investment, facilities and Australasian backing with some of the best brains in the regenerative medicine world make us the leader in NZ’s developing industry.

PESC treatment shows cartilage regenerating reversing damage caused by degenerative conditions. 

There is a perception that stem cell treatment is expensive

With us, one joint is $12,650 and two of the same joint is $15,300 including GST.

Single knee joint surgery is between $21,000-29,000.

Because we have both a clinic and a lab and control our own procedures from extraction to expansion, we can store patients’ excess cells for further treatments on other joints in years to come. There is no need for future lipoharvests.

Is treatment covered by insurance or ACC?

 As of late 2019, ACC are no longer covering the cost of the initial consultation but a big breakthrough for ReGen early in 2019 saw two insurers in NZ accept our patients’ claims for Expanded Stem Cell Therapy.

This is a first in NZ and Australia.

In 2020 we have seen more procedures covered and are hopeful that our good results and positive feedback from our clients will continue to see us partner with insurers.

This is a major breakthrough for ReGen and all those suffering from debilitating conditions as this means that PESC therapy may soon be recognised as an alternative to surgery.

It is a very positive sign showing the potential of regenerative medicine which will mean expanded stem cell therapy will become a commonplace treatment in the future.

What are mesenchymal stem cells?

Mesenchymal stem cells (MSCs, also sometimes called mesenchymal stromal cells) are somewhat confusing, because although they currently mean adult stem cells from non-blood tissues, some people are also starting to use it to mean the similar cells derived from induced pluripotent stem cells to create multipotent cells that can differentiate into bone, muscle, cartilage and fat.

In simple terms, stem cells are cells that have the potential to develop into many different cell types in the body.  We use your own fat cells as they can develop into any needed cell type, unlike bone marrow cells. They serve as a repair system and can in our specialised lab be multiplied into millions of cells. When placed in a joint they can stimulate the cartilage.

Where do you get the stem cells from?

We get them from your own fat in a process called harvesting the cells. When cells come from your own body they are known as autologous. This minimises the risk of rejection because we start with your own cells. At ReGen we only use a patient’s own cells.

What happens if I suffer from anxiety or don't like needles?

Some of our patients undergoing stem cell therapy suffer extreme nervousness, anxiety or have a fear of needles. It is usual for patients to be given pain medication to take prior to the procedure but for those patients  suffering with anxiety we can offer additional pain relief directly before the during procedure.

Nitrous oxide is a colourless gas that is commonly used by dentists and doctors for sedation and pain relief for patients undergoing minor medical procedures.

Our patients have found the gas option a great comfort as it makes them more relaxed so they can cope better with any discomfort during the procedure. If you suffer from anxiety or nervousness around needles then this option is available.

 What is the process of harvesting stem cells?

A qualified specialist will take the fat sample in an accredited operating theatre under local anesthesia. The process taking around an hour. In our Queenstown laboratory, the mesenchymal stem cells are extracted, purified and expanded. There’s very little pain involved in the stem cell harvest, dissolving stitches are used. Patients need to avoid anti-inflammatory medicines like ibuprofren or voltaran or celebrex for two weeks prior to the procedure. 

What is PESC (pure expanded stem cells)?

Our proprietary process means the Mesenchymal stem cells are extracted, purified and not mixed with any other types of stem cells. Expanded means the cells are multiplied and cultured to as many as are needed for your particular case.  We typically grow up to 100 million cells for a single joint. Those millions of mesenchymal stem cells represent the most concentrated form of stem cells available in the market today.

Am I a candidate for stem cell therapy?

If you have osteoarthritis or injury that has not recovered and continues to cause pain, you may be. While there is a lot of information on our site, it may be best to ring the clinic and talk through your own requirements. We can advise whether a consult with Dr Mubark would be beneficial. If you are pregnant or have active cancer, stem cell therapy is contraindicated.

Will insurance cover stem cell therapy?

In early 2019 two insurance companies covered the cost of our PESC therapy. Please contact your insurer to see if you qualify. 

What happens after my expanded stem cell therapy?

After the injection, there may be some minor pain and swelling. Minor inflammation occurs as part of the healing process when the cartilage interacts with stem cells, potentially stimulating cartilage growth. Crutches will be provided to knee patients. Avoid applying ice after the procedure as this can damage cells. A prescription for pain medication will be provided. Paracetamol is recommended. No anti-inflammatory medicines like ibuprofren or voltaran or celebrex should be taken for 4 weeks as this will reduce the potency of the stem cells.

How to achieve optimal results after stem cell therapy?

After the injection, we recommend a week’s rest and a joint brace. During your initial consultation, the doctor will determine which of the brace types we offer is recommended. We also have partnered with selected physiotherapists to develop a dedicated rehabilitation program. This is specially designed to integrate the stem cells into your joints and to keep the area stable. You can return to normal walking after two weeks. After a month you can run and resume full activities. Alignment braces should be used three months for support during weight-bearing activities.  We also recommend taking both Curcumin and Boswellia which are herbal supplements that reduce inflammation and increase healing and blood flow.

Can I travel after stem cell harvesting?

Yes. After the harvest we can cryo-store your cells for up to one year at no charge. When you return you can schedule your injection for a time that fits easily into your schedule.

Can you inject more than one joint or area in the same session?

Yes, we can. This will be discussed during the initial consult.  We commonly encounter two knees or two hips. In addition, multiple small joints in the hands and feet can be injected in one prolonged session. Any combination of areas to be treated together can be considered.

Can I have the fat sample and the stem cell injection all in Auckland?

Yes, you can. The initial consultation, harvest, and injection are all in Auckland. After your consult, you’ll be scheduled to have your fat sample taken in one of our many accredited operating theatres.  Your sample will be securely sent to our Queenstown laboratory for culturing.  When ready (6-8 weeks) we’ll contact you to schedule your injection appointment, in the same location as your first consult.

Do you guarantee success?

We only accept patients who show the best promise of a successful outcome. No therapy or intervention can guarantee 100% success. Our results across all PESC interarticular treatments show 70-90% reduction in pain, increased mobility and in some cases cartilage regeneration.

Are there risks with expanded stem cell treatment?

Complications are rare and minor.  The most common is pain and irritation at the injection site which lasts for 2-3 days.  Infection is rare as the sample is sterilized and sterile conditions are maintained during the injection.

Also is the potential for what is called a 'stem cell flare' post injection.

After your treatment where your expanded cells are injected into your area of pain or injury, in rare cases, stem cells release heat shock proteins.  This is the reaction of the stem cells when injected near inflamed tissue.

This can be quite painful and the joint will appear more inflamed and stiff than before the injection. If this occurs please telephone the clinic so that we can arrange for a higher level of pain relief. This discomfort only remains for around 24 to 48 hours.

This flare reaction is seen as a positive as it indicates the patient’s stem cells are in the right place and doing their job.

Do stem cells regrow cartilage in all patients? 

Our proprietary PESC therapy contains the highest dosage of MSCs in any therapy today.

We use the best injecting techniques under ultrasound guidance to ensure the cells are injected deep into the joints or affected area by our experienced doctor. The regrowth of cartilage takes some time and we recommend redoing scans at 6-12 months after therapy. PESC provide other results in addition to potential regrowth.  Over 80% of patients report less stiffness, reduced pain and improved range of motion.

Can stem cells be stored and how much does it cost?

Yes. As part of your treatment package, we store your cells in cryopreservation for 1 year free of charge. We can keep them securely stored for up to 15 years at an annual cost of $350 incl GST billed annually.  The upside is that the younger you have your original treatment the younger your cells remain in cryostorage and these younger stem cells will be available if needed in the future.

Can you repeat the process of injecting the same area or another area in the future and does it cost me anything?

If the original cells have been stored with us, we can repeat the injection for up to 15 years. As the cells will need to be expanded into a number big enough for regeneration, there will cost involved.

Do you inject stem cells into the spine?

No, not at this stage. Currently, we do all upper and lower limbs, as well as large, medium and small joints.